GproteinDb

intepirdine

Agent/drug
Bioactivity

intepirdine

SMILES	O=S(=O)(c1ccccc1)c1cnc2c(N3CCNCC3)cccc2c1
InChIKey	JJZFWROHYSMCMU-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	5
Hydrogen bond donors	1
Rotatable bonds	3
Molecular weight (Da)	353.1

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids DrugBank GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	5.62	6.27	7.58	ChEMBL
5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pKi	7.58	7.58	7.58	ChEMBL
5-HT₆	5HT6R	Human	5-Hydroxytryptamine	A	pKi	9.77	9.77	9.77	Guide to Pharmacology
5-HT₆	5HT6R	Rat	5-Hydroxytryptamine	A	pKi	9.63	9.63	9.63	ChEMBL
5-HT₆	5HT6R	Human	5-Hydroxytryptamine	A	pKi	8.85	9.37	9.78	ChEMBL
5-HT₇	5HT7R	Human	5-Hydroxytryptamine	A	pKi	4.85	4.85	4.85	ChEMBL
D₂	DRD2	Human	Dopamine	A	pKi	6.00	6.00	6.00	ChEMBL

Showing 1 to 7 of 7 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT₆	5HT6R	Human	5-Hydroxytryptamine	A	pIC50	7.01	8.16	8.55	ChEMBL

Showing 1 to 1 of 1 entry

intepirdine

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	Yes

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids DrugBank GPCRdb

Compound is not listed as a drug.