CHEMBL81485


SMILES CNCC1CC2c3ccccc3Cc3ccccc3N2O1
InChIKey LCKBEOTXTNWYRG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 280.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 7.73 7.73 7.73 ChEMBL
H1 HRH1 Human Histamine A pIC50 7.97 7.97 7.97 ChEMBL
D4 DRD4 Human Dopamine A pIC50 6.52 6.52 6.52 ChEMBL
α1A ADA1A Human Adrenoceptors A pIC50 6.72 6.72 6.72 ChEMBL
α2A ADA2A Human Adrenoceptors A pIC50 6.36 6.36 6.36 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 8.15 8.15 8.15 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 7.88 7.88 7.88 ChEMBL
D2 DRD2 Human Dopamine A pIC50 5.77 5.77 5.77 ChEMBL
D3 DRD3 Human Dopamine A pIC50 6.47 6.47 6.47 ChEMBL