GproteinDb

FENOFIBRATE

Agent/drug
Bioactivity

FENOFIBRATE

SMILES	CC(C)OC(=O)C(C)(C)Oc1ccc(C(=O)c2ccc(Cl)cc2)cc1
InChIKey	YMTINGFKWWXKFG-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	0
Rotatable bonds	6
Molecular weight (Da)	360.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb
Structure pdb	8K8J

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

β₃	ADRB3	Human	Adrenoceptors	A	pKi	4.03	4.03	4.03	ChEMBL
β₃	ADRB3	Human	Adrenoceptors	A	pKi	8.39	8.39	8.39	Drug Central
5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pKi	6.22	6.22	6.22	ChEMBL
5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pKi	8.21	8.21	8.21	Drug Central
5-HT_2C	5HT2C	Human	5-Hydroxytryptamine	A	pKi	5.91	5.91	5.91	ChEMBL
5-HT_2C	5HT2C	Human	5-Hydroxytryptamine	A	pKi	8.23	8.23	8.23	Drug Central
A₃	AA3R	Human	Adenosine	A	pKi	5.49	5.49	5.49	ChEMBL
A₃	AA3R	Human	Adenosine	A	pKi	8.26	8.26	8.26	Drug Central
D₃	DRD3	Human	Dopamine	A	pKi	4.33	4.33	4.33	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	8.36	8.36	8.36	Drug Central

Showing 1 to 10 of 10 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pIC50	5.67	5.67	5.67	ChEMBL
5-HT_2C	5HT2C	Human	5-Hydroxytryptamine	A	pIC50	5.62	5.62	5.62	ChEMBL
A₃	AA3R	Human	Adenosine	A	pIC50	5.24	5.24	5.24	ChEMBL
M₁	ACM1	Rat	Acetylcholine (muscarinic)	A	Potency	7.20	7.20	7.20	ChEMBL
NPS	NPSR1	Human	Neuropeptide S	A	Potency	4.80	4.80	4.80	ChEMBL
TSH	TSHR	Human	Glycoprotein hormone	A	Potency	4.80	4.85	4.90	ChEMBL

Showing 1 to 6 of 6 entries

FENOFIBRATE

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb
Structure pdb	8K8J

Compound is not listed as a drug.