CHEMBL59262


SMILES O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(c2cc(Cl)ccc2Cl)CC1
InChIKey IVMAVCHNIRPHMA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 451.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Rat Adrenoceptors A pKi 9.17 9.17 9.17 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 8.27 8.27 8.27 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKi 8.74 8.74 8.74 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 8.84 8.84 8.84 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.58 7.58 7.58 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database