CHEMBL92924


SMILES COc1cc(NC(=O)C2CC2)c(Cl)cc1C(=O)N[C@H]1CCN(C2C3CC4CC(C3)CC2C4)C1
InChIKey UYRXOOUBRAEWNZ-OBBCFLIVSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 471.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 8.77 8.77 8.77 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.96 6.96 6.96 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.36 8.36 8.36 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database