(S)-4C3HPG


SMILES N[C@@H](c1ccc(c(c1)O)C(=O)O)C(=O)O
InChIKey GXZSAQLJWLCLOX-ZETCQYMHSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 3
Molecular weight (Da) 211.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu1 GRM1 Human Metabotropic glutamate C pKi 5.8 5.9 6.0 Guide to Pharmacology
mGlu2 GRM2 Rat Metabotropic glutamate C pKi 4.8 4.8 4.8 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu1 GRM1 Rat Metabotropic glutamate C pIC50 4.4 4.4 4.4 ChEMBL
mGlu1 GRM1 Human Metabotropic glutamate C pIC50 4.4 4.4 4.4 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pEC50 4.32 4.32 4.32 ChEMBL
mGlu5 GRM5 Rat Metabotropic glutamate C pIC50 5.6 5.6 5.6 Guide to Pharmacology