CHEMBL98299


SMILES Cn1ncnc1-c1ccc2c(c1)c(C1CCN(CCN3CCNC3=O)CC1)cn2-c1ccc(F)cc1
InChIKey CLSRMUGSDHADPG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 487.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 6.72 6.72 6.72 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 8.19 8.19 8.19 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.22 7.22 7.22 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.96 7.96 7.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database