(R)-4-(3-(2-Amino-4-(4-Fluorophenyl)Thiazol-5-Yl)Pyrrolidin-1-Yl)-1-(4-Fluorophenyl)Butan-1-One

Chemical Properties

SMILES C1CN(CC1C2=C(N=C(S2)N)C3=CC=C(C=C3)F)CCCC(=O)C4=CC=C(C=C4)F
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight 427.2

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey PMIAIKWRXUGRQG-UHFFFAOYSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Mouse 5-Hydroxytryptamine A pKi 7.72 7.72 7.72 PDSP KiDatabase