(R)-4-(3-(2-Amino-4-(4-Fluorophenyl)Thiazol-5-Yl)Pyrrolidin-1-Yl)-1-(4-Fluorophenyl)Butan-1-One
Chemical Properties
| SMILES | C1CN(CC1C2=C(N=C(S2)N)C3=CC=C(C=C3)F)CCCC(=O)C4=CC=C(C=C4)F |
| Hydrogen bond acceptors | 5 |
| Hydrogen bond donors | 1 |
| Rotatable bonds | 7 |
| Molecular weight | 427.2 |
Drug Properties
| Type | Small molecule |
| Endogenous | No |
| Approved | No |
| InChIKey | PMIAIKWRXUGRQG-UHFFFAOYSA-N |
Database Connections
| External Links |
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Bioactivity
| Receptor | Experimental Data | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| 5-HT2A | 5HT2A | Mouse | 5-Hydroxytryptamine | A | pKi | 7.72 | 7.72 | 7.72 | PDSP KiDatabase |