CHEMBL74467


SMILES CS(=O)(=O)c1ccc(F)cc1NCC1=NCCN1
InChIKey YYHDOUOUAFMQDK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 271.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 5.88 5.88 5.88 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 5.58 5.58 5.58 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 6.09 6.09 6.09 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 5.35 5.35 5.35 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2C ADA2C Human Adrenoceptors A pEC50 5.7 5.7 5.7 ChEMBL
α1A ADA1A Human Adrenoceptors A pEC50 7.78 7.78 7.78 ChEMBL