Desmethylsertraline


SMILES C1CC(C2=CC=CC=C2C1C3=CC(=C(C=C3)Cl)Cl)N
InChIKey SRPXSILJHWNFMK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 291.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Human Histamine A pKi 5.05 5.05 5.05 PDSP Ki database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.0 5.0 5.0 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 5.0 5.0 5.0 PDSP Ki database
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 5.78 5.78 5.78 PDSP Ki database
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 5.46 5.46 5.46 PDSP Ki database
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 5.51 5.51 5.51 PDSP Ki database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 5.42 5.42 5.42 PDSP Ki database
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 5.48 5.48 5.48 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database