Fluoxetine-R-(-)


SMILES CNCCC(C1=CC=CC=C1)OC2=CC=C(C=C2)C(F)(F)F.Cl
InChIKey GIYXAJPCNFJEHY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 345.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 5.0 5.0 5.0 PDSP Ki database
5-HT1B 5HT1B Rat 5-Hydroxytryptamine A pKi 5.0 5.0 5.0 PDSP Ki database
5-HT1D F1MMU1 Bovine 5-Hydroxytryptamine A pKi 5.0 5.0 5.0 PDSP Ki database
5-HT2C A0A4W2GLI9 Hybrid cattle 5-Hydroxytryptamine A pKi 6.81 6.81 6.81 PDSP Ki database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.19 7.19 7.19 PDSP Ki database
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 6.0 6.0 6.0 PDSP Ki database
H1 HRH1 Guinea pig Histamine A pKi 6.09 6.09 6.09 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database