Perospirone


SMILES C1CCC2C(C1)C(=O)N(C2=O)CCCCN3CCN(CC3)C4=NSC5=CC=CC=C54
InChIKey FBVFZWUMDDXLLG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 426.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pKi 9.22 9.22 9.22 PDSP Ki database
D4 DRD4 Human Dopamine A pKi 10.05 10.05 10.05 PDSP Ki database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 9.15 9.15 9.15 PDSP Ki database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 5.97 5.97 5.97 PDSP Ki database
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 7.7 7.7 7.7 PDSP Ki database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 9.36 9.36 9.36 PDSP Ki database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 8.54 8.54 8.54 PDSP Ki database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 8.28 8.28 8.28 PDSP Ki database
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 6.49 6.49 6.49 PDSP Ki database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.32 6.32 6.32 PDSP Ki database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.42 8.42 8.42 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database