GproteinDb

JP1302

Agent/drug
Bioactivity

JP1302

SMILES	CN1CCN(c2ccc(Nc3c4ccccc4nc4ccccc34)cc2)CC1
InChIKey	QZKGUNQLVFEEBA-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	1
Rotatable bonds	3
Molecular weight (Da)	368.2

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

α_1A	ADA1A	Human	Adrenoceptors	A	pKi	5.80	5.80	5.80	ChEMBL
α_1B	ADA1B	Human	Adrenoceptors	A	pKi	5.57	5.57	5.57	ChEMBL
α_1D	ADA1D	Human	Adrenoceptors	A	pKi	5.76	5.76	5.76	ChEMBL
α_2A	ADA2A	Human	Adrenoceptors	A	pKi	5.50	5.57	5.64	ChEMBL
α_2B	ADA2B	Human	Adrenoceptors	A	pKi	5.76	5.79	5.82	ChEMBL
α_2C	ADA2C	Human	Adrenoceptors	A	pKi	7.40	7.50	7.55	ChEMBL
β₂	ADRB2	Human	Adrenoceptors	A	pKi	6.09	6.09	6.09	ChEMBL
5-HT_1D	5HT1D	Human	5-Hydroxytryptamine	A	pKi	5.79	5.79	5.79	ChEMBL
5-HT₆	5HT6R	Human	5-Hydroxytryptamine	A	pKi	6.42	6.42	6.42	ChEMBL
5-HT₇	5HT7R	Human	5-Hydroxytryptamine	A	pKi	6.38	6.38	6.38	ChEMBL
D₁	DRD1	Human	Dopamine	A	pKi	5.34	5.34	5.34	ChEMBL
H₁	HRH1	Human	Histamine	A	pKi	6.39	6.39	6.39	ChEMBL
H₃	HRH3	Human	Histamine	A	pKi	7.08	7.08	7.08	ChEMBL
M₁	ACM1	Human	Acetylcholine (muscarinic)	A	pKi	6.14	6.14	6.14	ChEMBL
M₂	ACM2	Human	Acetylcholine (muscarinic)	A	pKi	6.69	6.69	6.69	ChEMBL

Showing 1 to 15 of 15 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

α_2C	ADA2C	Human	Adrenoceptors	A	pKB	6.90	7.35	7.80	Guide to Pharmacology
apelin	APJ	Human	Apelin	A	pIC50	5.45	5.45	5.45	ChEMBL
GPR65	PSYR	Human	A orphans	A	pEC50	5.90	5.90	5.90	ChEMBL

Showing 1 to 3 of 3 entries

JP1302

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Clinical Trials

Phase I 0

Phase II 0

Phase III 0

Approved No

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb

Compound is not listed as a drug.