CHEMBL60444


SMILES NCCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](CCCN=C(N)N)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O
InChIKey UEVAHGMTRWGMTB-JBXUNAHCSA-N

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Protein
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Rat Opioid A pKi 8.77 8.93 9.42 ChEMBL
δ OPRD Human Opioid A pKi 4.72 4.72 4.72 ChEMBL
κ OPRK Human Opioid A pKi 5.37 5.37 5.37 ChEMBL
μ OPRM Human Opioid A pKi 9.85 9.85 9.85 ChEMBL
κ OPRK Guinea pig Opioid A pKi 5.37 5.37 5.37 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Mouse Opioid A pIC50 6.11 6.11 6.11 ChEMBL
δ OPRD Mouse Opioid A pIC50 6.11 6.11 6.11 ChEMBL