RENZAPRIDE
SMILES | COC1=CC(=C(C=C1C(=O)NC2CCN3CCCC2C3)Cl)N.Cl |
InChIKey | WYONTPMGUQWRKN-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 4 |
Hydrogen bond donors | 2 |
Rotatable bonds | 3 |
Molecular weight (Da) | 359.1 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
5-HT4 | 5HT4R | Rat | 5-Hydroxytryptamine | A | pKi | 6.6 | 6.93 | 7.6 | PDSP Ki database |
5-HT7 | 5HT7R | Rat | 5-Hydroxytryptamine | A | pKi | 6.0 | 6.0 | 6.0 | PDSP Ki database |
5-HT4 | 5HT4R | Mouse | 5-Hydroxytryptamine | A | pKi | 6.88 | 6.98 | 7.01 | PDSP Ki database |
5-HT4 | 5HT4R | Human | 5-Hydroxytryptamine | A | pKi | 6.6 | 6.68 | 6.76 | PDSP Ki database |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |