trans-1-(4-chlorophenyl)-6-(2,4-dichlorophenyl)-3-(3,4-difluorobenzyl)piperidin-2-one


SMILES C1CC(N(C(=O)C1CC2=CC(=C(C=C2)F)F)C3=CC=C(C=C3)Cl)C4=C(C=C(C=C4)Cl)Cl
InChIKey JUMFPWRWLUZHBS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 479.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB1 CNR1 Human Cannabinoid A pKi 6.96 6.96 6.96 PDSP Ki database
CB2 CNR2 Human Cannabinoid A pKi 5.78 5.78 5.78 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database