cis-1,2-bis(4-chlorophenyl)-5-(3,4-difluorobenzyl)piperidine


SMILES C1CC(N(CC1CC2=CC(=C(C=C2)F)F)C3=CC=C(C=C3)Cl)C4=CC=C(C=C4)Cl
InChIKey DZOXGRZPPMWLSR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 431.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB1 CNR1 Human Cannabinoid A pKi 5.79 6.46 7.14 PDSP Ki database
CB2 CNR2 Human Cannabinoid A pKi 5.73 5.74 5.75 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database