CHEMBL5085974


SMILES CN(C)C(=O)C(CCN1CCN(c2cccc(Cl)c2Cl)CC1)(c1ccccc1)c1ccccc1
InChIKey GCEDZTWELCPACO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Na
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 6.99 6.99 6.99 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.5 6.63 6.77 ChEMBL
μ OPRM Human Opioid A pKi 9.08 9.08 9.08 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.13 7.31 7.5 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pEC50 6.13 6.13 6.13 ChEMBL
μ OPRM Human Opioid A pEC50 6.58 7.19 7.91 ChEMBL