CHEMBL133868


SMILES CC(N)Cc1c[nH]c2ccc3c(c12)CCCO3
InChIKey VVHJUSGIUWQPIT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 230.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Rat Adrenoceptors A pKi 5.0 5.0 5.0 ChEMBL
5-HT4 5HT4R Human 5-Hydroxytryptamine A pKi 5.75 5.75 5.75 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 5.72 5.72 5.72 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 4.62 4.62 4.62 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.89 7.89 7.89 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.4 6.4 6.4 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 8.26 8.26 8.26 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.44 8.44 8.44 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 4.96 4.96 4.96 ChEMBL