CHEMBL1256344


SMILES CCOC(=O)C(C)N1C(=O)N(CC(O)CN2CCN(c3ccccc3OC)CC2)C(c2ccccc2)(c2ccccc2)C1=O
InChIKey AVGWWHGGUIZHBV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 11
Molecular weight (Da) 600.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Rat Adrenoceptors A pKd 7.15 7.15 7.15 ChEMBL
α1B ADA1B Human Adrenoceptors A pKd 5.96 5.96 5.96 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKd 7.19 7.19 7.19 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKi 6.87 6.87 6.87 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database