CHEMBL1257810


SMILES O=C(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1cc2ccc1CCc1ccc(cc1)CC2
InChIKey SBJOJKQLHNFZTE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 487.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 5.01 5.01 5.01 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.41 7.41 7.41 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.77 7.77 7.77 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.68 7.79 7.89 ChEMBL
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 5.62 5.62 5.62 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database