CHEMBL1257883


SMILES CN1C(=O)N(CC(O)CN2CCN(c3ccccc3F)CC2)C(c2ccccc2)(c2ccccc2)C1=O
InChIKey ZTMOGXXMLUCQMX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 502.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Rat Adrenoceptors A pKd 6.61 6.61 6.61 ChEMBL
α1B ADA1B Human Adrenoceptors A pKd 5.74 5.74 5.74 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKd 6.05 6.05 6.05 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKi 6.25 6.25 6.25 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database