Ligand Data

Ligand

id 24316
Name CHEMBL1332346
SMILES COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@H]2c3cc(C(=O)N(C)C)n(Cc4ccccc4)c3C[C@H]2CN1C(=O)c1ccccc1
InChIKey YOHQXMCAKJZZPA-XRCYRVQWSA-N
Type small-molecule
External Links

Structure

Properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight 579.3


Bioactivity

Receptor Affinity (nM) Potency (nM)
GTP Uniprot Species Family Class Min Avg Max Min Avg Max
NPBW1 NPBW1 Human Neuropeptide W/neuropeptide B A (Rhodopsin) 16295 16295 16295
MCH1 MCHR1 Human Melanin-concentrating hormone A (Rhodopsin) 11115 11115 11115
TSH TSHR Human Glycoprotein hormone A (Rhodopsin) 10000 10000 10000