CHEMBL1258228


SMILES COC(=O)CN1C(=O)N(CC(O)CN2CCN(c3ccccc3)CC2)C(c2ccccc2)(c2ccccc2)C1=O
InChIKey ZJFVRVHCJJOACM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 542.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Rat Adrenoceptors A pKd 5.36 5.36 5.36 ChEMBL
α1B ADA1B Human Adrenoceptors A pKd 5.44 5.44 5.44 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKd 5.86 5.86 5.86 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKi 6.38 6.38 6.38 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database