CHEMBL1258987


SMILES CN1CCN(C2Cc3ccccc3Sc3ccc(-c4cnn(C)c4)cc32)CC1
InChIKey MKRIRFBTLSNVCR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 390.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Golden hamster Adrenoceptors A pKi 9.7 9.7 9.7 ChEMBL
α1A ADA1A Bovine Adrenoceptors A pKi 9.62 9.62 9.62 ChEMBL
α1D ADA1D Rat Adrenoceptors A pKi 8.85 8.85 8.85 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.64 8.64 8.64 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database