RWJ-68157


SMILES CC(C)Oc1ccccc1N1CCN(CCNC(=O)CN2CCCCCC2=O)CC1
InChIKey XHBOWUOETHUEOP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 416.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 5.45 5.45 5.45 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 6.3 6.3 6.3 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.66 7.71 7.75 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database