CHEMBL126667


SMILES Fc1ccc(OCCCN2CCc3ccccc3C2)cc1
InChIKey UQNXMCNVFPEPNB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 285.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 7.08 7.08 7.08 ChEMBL
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 6.4 6.4 6.4 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.0 7.0 7.0 ChEMBL
H1 HRH1 Human Histamine A pKi 6.42 6.42 6.42 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.11 6.11 6.11 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.49 6.49 6.49 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.61 6.61 6.61 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.25 6.25 6.25 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.78 6.78 6.78 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database