MT-1207


SMILES C12=CC=CC=C1SN=C2N3CCN(CCCCN4N=NC5=C4C=CC=C5)CC3
InChIKey GOALZWVIJQGFQJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 392.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 10.1 10.1 10.1 Guide to Pharmacology
α1B ADA1B Human Adrenoceptors A pKi 10.07 10.07 10.07 Guide to Pharmacology
α1D ADA1D Human Adrenoceptors A pKi 9.16 9.16 9.16 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 9.54 9.54 9.54 Guide to Pharmacology
α1A ADA1A Human Adrenoceptors A pIC50 10.0 10.0 10.0 Guide to Pharmacology
α1B ADA1B Human Adrenoceptors A pIC50 9.82 9.82 9.82 Guide to Pharmacology
α1D ADA1D Human Adrenoceptors A pIC50 8.85 8.85 8.85 Guide to Pharmacology