N-propylnorapomorphine


SMILES CCCN1CCc2c3C1Cc1ccc(c(c1c3ccc2)O)O
InChIKey BTGAJCKRXPNBFI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 295.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pKi 5.47 5.8 6.14 PDSP Ki database
D1 DRD1 Human Dopamine A pKi 5.74 5.74 5.74 PDSP Ki database
D1 DRD1 Human Dopamine A pKi 7.4 7.4 7.4 Guide to Pharmacology
D2 DRD2 Human Dopamine A pKi 5.62 7.17 8.05 PDSP Ki database
D4 DRD4 Human Dopamine A pKi 8.4 8.4 8.4 PDSP Ki database
D5 DRD5 Human Dopamine A pKi 5.94 5.94 5.94 PDSP Ki database
D5 DRD5 Human Dopamine A pKi 5.9 5.9 5.9 Guide to Pharmacology
D3 DRD3 Rat Dopamine A pKi 9.09 9.09 9.09 PDSP Ki database
D2 DRD2 Mouse Dopamine A pKi 8.15 8.27 8.39 PDSP Ki database
D2 DRD2 Dog Dopamine A pKi 9.4 9.4 9.4 PDSP Ki database
D2 DRD2 Rat Dopamine A pKi 8.32 8.32 8.32 PDSP Ki database
D1 DRD1 Mouse Dopamine A pKi 6.32 6.32 6.32 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database