GproteinDb

PAF

Agent/drug
Bioactivity

PAF

SMILES	CCCCCCCCCCCCCCCCOC[C@H](COP(=O)([O-])OCC[N+](C)(C)C)OC(C)=O
InChIKey	HVAUUPRFYPCOCA-AREMUKBSSA-N

Chemical Properties

Hydrogen bond acceptors	7
Hydrogen bond donors	0
Rotatable bonds	25
Molecular weight (Da)	523.4

Database connections

Guide To Pharmacology DrugBank ChEMBL_compound_ids PubChem GPCRdb
Structure pdb	8XYD

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

α_1B	ADA1B	Human	Adrenoceptors	A	pKi	5.35	5.35	5.35	ChEMBL
α_1D	ADA1D	Human	Adrenoceptors	A	pKi	5.69	5.69	5.69	ChEMBL
5-HT_1D	5HT1D	Human	5-Hydroxytryptamine	A	pKi	5.07	5.07	5.07	ChEMBL
5-HT_2C	5HT2C	Human	5-Hydroxytryptamine	A	pKi	5.51	5.51	5.51	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	5.75	5.75	5.75	ChEMBL
PAF	PTAFR	Human	Platelet-activating factor	A	pKi	7.50	7.70	7.90	Guide to Pharmacology
PAF	PTAFR	Human	Platelet-activating factor	A	pKd	8.80	8.85	8.90	Guide to Pharmacology
PAF	PTAFR	Human	Platelet-activating factor	A	pKi	9.82	9.82	9.82	ChEMBL

Showing 1 to 8 of 8 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

PAF	PTAFR	Human	Platelet-activating factor	A	pIC50	8.20	8.20	8.20	Guide to Pharmacology
PAF	PTAFR	Human	Platelet-activating factor	A	pIC50	9.55	9.55	9.55	ChEMBL

Showing 1 to 2 of 2 entries

PAF

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Endogenous
Approved drug	Yes

Clinical Trials

Phase I 0

Phase II 0

Phase III 0

Approved No

Database connections

Guide To Pharmacology DrugBank ChEMBL_compound_ids PubChem GPCRdb
Structure pdb	8XYD

Compound is not listed as a drug.