piboserod


SMILES CCCCN1CCC(CC1)CNC(=O)c1c2OCCCn2c2c1cccc2
InChIKey KVCSJPATKXABRQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 369.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT4 5HT4R Human 5-Hydroxytryptamine A pKi 8.8 9.61 10.28 ChEMBL
5-HT4 5HT4R Guinea pig 5-Hydroxytryptamine A pKi 8.8 8.8 8.8 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.449999999999999 6.45 6.45 Guide to Pharmacology
5-HT4 5HT4R Human 5-Hydroxytryptamine A pKi 8.8 9.6 10.4 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT4 5HT4R Human 5-Hydroxytryptamine A pIC50 9.2 9.2 9.2 ChEMBL