GproteinDb

PSB-KD107

Agent/drug
Bioactivity

PSB-KD107

SMILES	Cn1c(=O)c2c(nc3n2CCCN3CCc2c[nH]c3ccccc23)n(C)c1=O
InChIKey	PUJKERUFRDZALE-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	7
Hydrogen bond donors	1
Rotatable bonds	3
Molecular weight (Da)	378.2

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

A₁	AA1R	Rat	Adenosine	A	pKi	4.60	4.60	4.60	ChEMBL
A₁	AA1R	Human	Adenosine	A	pKi	5.00	5.00	5.00	PDSP Ki database
A_2A	AA2AR	Rat	Adenosine	A	pKi	6.48	6.48	6.48	ChEMBL
A_2A	AA2AR	Human	Adenosine	A	pKi	5.34	5.34	5.34	ChEMBL
A_2A	AA2AR	Human	Adenosine	A	pKi	5.34	5.34	5.34	PDSP Ki database
A_2B	AA2BR	Human	Adenosine	A	pKi	5.00	5.00	5.00	ChEMBL
A_2B	AA2BR	Human	Adenosine	A	pKi	5.00	5.00	5.00	PDSP Ki database
A₃	AA3R	Human	Adenosine	A	pKi	5.00	5.00	5.00	PDSP Ki database

Showing 1 to 8 of 8 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

GPR18	GPR18	Human	GPR18, GPR55 and GPR119	A	pEC50	6.25	6.25	6.25	Guide to Pharmacology
GPR18	GPR18	Human	GPR18, GPR55 and GPR119	A	pEC50	6.25	6.25	6.25	ChEMBL
GPR18	GPR18	Human	GPR18, GPR55 and GPR119	A	pIC50	6.03	6.03	6.03	ChEMBL

Showing 1 to 3 of 3 entries

PSB-KD107

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Clinical Trials

Phase I 0

Phase II 0

Phase III 0

Approved No

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb

Compound is not listed as a drug.