CHEMBL14199


SMILES COc1ccccc1N1CCN(CCCn2c(=O)[nH]c3scc(-c4ccccc4)c3c2=O)CC1
InChIKey MOYXTVNKHXOQKG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 476.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Bovine Adrenoceptors A pKi 8.9 8.9 8.9 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 7.8 7.8 7.8 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKi 8.02 8.02 8.02 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 8.15 8.15 8.15 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 8.07 8.07 8.07 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database