Ligand Data
Ligand
Name | CHEMBL1424299 |
SMILES | COc1ccc(-c2nnc(SCC(=O)N(Cc3ccccc3)C(C)(C)C)o2)cc1OC |
InChIKey | LPNHFMYVRCKDFF-UHFFFAOYSA-N |
Type | small-molecule |
External Links |
Structure
Properties
Hydrogen bond acceptors | 7 |
Hydrogen bond donors | 0 |
Rotatable bonds | 8 |
Molecular weight | 441.2 |
Bioactivity
Receptor | Affinity (nM) | Potency (nM) | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Min | Avg | Max | Min | Avg | Max |
TSH | TSHR | Human | Glycoprotein hormone | A (Rhodopsin) | 31623 | 31623 | 31623 |