senktide
| SMILES | None |
| InChIKey | HMHYXLVEFVGOPM-QKUYTOGTSA-N |
| Sequence | DFFGLM |
Chemical properties
| Hydrogen bond acceptors | None |
| Hydrogen bond donors | None |
| Rotatable bonds | None |
| Molecular weight (Da) |
Drug properties
| Molecular type | Peptide |
| Endogenous/Surrogate | Surrogate |
| Approved drug | No |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| NK3 | NK3R | Human | Tachykinin | A | pKi | 8.5 | 8.5 | 8.5 | ChEMBL |
| NK3 | NK3R | Human | Tachykinin | A | pKi | 7.1 | 7.85 | 8.6 | Guide to Pharmacology |
| NK3 | NK3R | Rat | Tachykinin | A | pKd | 7.9 | 8.5 | 9.1 | Guide to Pharmacology |
| NK3 | NK3R | Mouse | Tachykinin | A | pKi | 7.6 | 7.8 | 8.0 | Guide to Pharmacology |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| NK3 | NK3R | Rat | Tachykinin | A | pIC50 | 7.96 | 7.96 | 7.96 | ChEMBL |
| NK3 | NK3R | Rat | Tachykinin | A | pEC50 | 7.89 | 9.28 | 10.64 | ChEMBL |
| NK1 | NK1R | Guinea pig | Tachykinin | A | pEC50 | 4.46 | 4.46 | 4.46 | ChEMBL |
| NK3 | NK3R | Human | Tachykinin | A | pIC50 | 7.25 | 7.8 | 9.0 | ChEMBL |
| NK3 | NK3R | Human | Tachykinin | A | pEC50 | 7.96 | 8.21 | 8.52 | ChEMBL |
| NK3 | NK3R | Rat | Tachykinin | A | pEC50 | 7.9 | 8.35 | 8.8 | Guide to Pharmacology |
| NK3 | NK3R | Guinea pig | Tachykinin | A | pIC50 | 7.92 | 7.92 | 7.92 | ChEMBL |
| NK3 | NK3R | Guinea pig | Tachykinin | A | pEC50 | 9.3 | 9.3 | 9.3 | Guide to Pharmacology |