CHEMBL138109


SMILES COc1cccc2c(CCCNCCOc3ccccn3)cccc12
InChIKey DFNUNBHMMOZMON-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 336.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 6.57 6.57 6.57 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 7.08 7.08 7.08 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.42 6.42 6.42 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.84 7.84 7.84 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 9.72 9.72 9.72 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 9.07 9.07 9.07 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database