GproteinDb

SEW2871

Agent/drug
Bioactivity

SEW2871

SMILES	FC(F)(F)c1cccc(-c2noc(-c3cc(-c4ccccc4)c(C(F)(F)F)s3)n2)c1
InChIKey	OYMNPJXKQVTQTR-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	0
Rotatable bonds	3
Molecular weight (Da)	440.0

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb
Structure pdb	7EW7

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

S1P₁	S1PR1	Human	Lysophospholipid (S1P)	A	pKi	5.50	6.60	7.70	Guide to Pharmacology

Showing 1 to 1 of 1 entry

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

S1P₁	S1PR1	Human	Lysophospholipid (S1P)	A	pEC50	7.54	7.72	7.90	Guide to Pharmacology
S1P₁	S1PR1	Mouse	Lysophospholipid (S1P)	A	pEC50	7.68	7.68	7.68	Guide to Pharmacology
S1P₁	S1PR1	Human	Lysophospholipid (S1P)	A	pIC50	7.43	7.43	7.43	ChEMBL
S1P₁	S1PR1	Human	Lysophospholipid (S1P)	A	pEC50	5.50	6.59	7.89	ChEMBL
S1P₅	S1PR5	Human	Lysophospholipid (S1P)	A	pIC50	5.34	5.34	5.34	ChEMBL

Showing 1 to 5 of 5 entries

SEW2871

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb
Structure pdb	7EW7

Compound is not listed as a drug.