SRA880


SMILES COc1cccc2c1C[C@H]1C[C@H](CN([C@@H]1C2)C)C(=O)N1CCN(CC1)c1ccc(cc1)[N+](=O)[O-]
InChIKey INULNSAIIZKOQE-YOSAUDMPSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 464.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
SST2 SSR2 Rat Somatostatin A pKd 5.11 5.11 5.11 ChEMBL
SST5 SSR5 Human Somatostatin A pKd 5.75 5.75 5.75 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKd 6.95 6.95 6.95 ChEMBL
β1 ADRB1 Human Adrenoceptors A pKd 6.65 6.65 6.65 ChEMBL
D4 DRD4 Human Dopamine A pKd 8.3 8.3 8.3 ChEMBL
SST1 SSR1 Human Somatostatin A pKd 7.99 7.99 7.99 ChEMBL
SST1 SSR1 Human Somatostatin A pKd 8.0 8.05 8.1 Guide to Pharmacology
SST2 SSR2 Human Somatostatin A pKd 4.44 4.44 4.44 ChEMBL
SST3 SSR3 Human Somatostatin A pKd 5.06 5.06 5.06 ChEMBL
SST4 SSR4 Human Somatostatin A pKd 4.82 4.82 4.82 ChEMBL
SST1 SSR1 Rat Somatostatin A pKd 9.15 9.15 9.15 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database