SRI22141


SMILES CN1CC[C@]23[C@H]4Oc5c(O)ccc(C[C@@H]1[C@@]2(Cc1c4ncc(c1)c1ccc(Cl)cc1)OCCCc1ccccc1)c35
InChIKey AQMQWKFSMIRRJA-OGICNVKRSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 564.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 8.29 8.29 8.29 Guide to Pharmacology
μ OPRM Human Opioid A pKi 7.71 7.71 7.71 Guide to Pharmacology
δ OPRD Human Opioid A pKi 8.98 8.98 8.98 ChEMBL
κ OPRK Human Opioid A pKi 8.81 8.81 8.81 ChEMBL
μ OPRM Human Opioid A pKi 9.27 9.27 9.27 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 8.89 8.89 8.89 Guide to Pharmacology
μ OPRM Human Opioid A pEC50 9.7 9.7 9.7 Guide to Pharmacology
δ OPRD Human Opioid A pEC50 9.57 9.57 9.57 ChEMBL
μ OPRM Human Opioid A pEC50 8.67 8.67 8.67 ChEMBL