CHEMBL138989


SMILES C[C@@H]1C[C@@H](C)N1C(=O)[C@@H]1C=C2c3cccc4[nH]cc(c34)CC2N(C)C1
InChIKey DUKNIHFTDAXJON-RCZCSUKSSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 335.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Mouse Dopamine A pKi 6.47 6.47 6.47 ChEMBL
5-HT1E 5HT1E Human 5-Hydroxytryptamine A pKi 6.85 6.85 6.85 ChEMBL
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 6.89 6.89 6.89 ChEMBL
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 7.89 7.89 7.89 ChEMBL
D5 DRD5 Human Dopamine A pKi 6.23 6.23 6.23 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 8.7 8.7 8.7 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.51 7.51 7.51 ChEMBL
H1 HRH1 Human Histamine A pKi 5.85 5.85 5.85 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.14 7.14 7.14 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.21 7.21 7.21 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.51 6.51 6.51 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.82 6.82 6.82 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.17 8.17 8.17 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.48 6.48 6.48 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database