VU0080241


SMILES CC1CCCN(C1)c1ncnc2c1cnn2c1ccc(cc1C)C
InChIKey CLQVVBPDAXJGBV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 321.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu4 GRM4 Human Metabotropic glutamate C pEC50 5.3 5.3 5.3 Guide to Pharmacology
mGlu1 GRM1 Rat Metabotropic glutamate C pIC50 5.58 5.58 5.58 ChEMBL
mGlu4 GRM4 Human Metabotropic glutamate C pEC50 5.34 5.34 5.34 ChEMBL
mGlu5 GRM5 Rat Metabotropic glutamate C pEC50 5.3 5.3 5.3 ChEMBL
NPS NPSR1 Human Neuropeptide S A Potency 5.0 5.0 5.0 ChEMBL