amthamine


SMILES NCCc1sc(nc1C)N
InChIKey LHVRFUVVRXGZPV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 157.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Structure pdb 8YUT

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 5.3 5.3 5.3 ChEMBL
H2 HRH2 Human Histamine A pKi 5.2 5.2 5.2 ChEMBL
H2 HRH2 Rat Histamine A pKd 4.94 4.94 4.94 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H2 HRH2 Human Histamine A pEC50 6.4 6.4 6.4 Guide to Pharmacology
H2 HRH2 Human Histamine A pEC50 6.72 6.72 6.72 ChEMBL
H1 HRH1 Human Histamine A pEC50 4.8 4.8 4.8 ChEMBL