anandamide


SMILES CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCCO
InChIKey LGEQQWMQCRIYKG-DOFZRALJSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 16
Molecular weight (Da) 347.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Endogenous
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB1 CNR1 Human Cannabinoid A pKi 6.3 6.65 7.0 Guide to Pharmacology
CB2 CNR2 Human Cannabinoid A pKi 5.7 6.05 6.4 Guide to Pharmacology
CB2 CNR2 Rat Cannabinoid A pKi 6.44 6.44 6.44 ChEMBL
CB1 CNR1 Rat Cannabinoid A pKi 5.24 6.79 7.66 ChEMBL
CB2 CNR2 Human Cannabinoid A pKi 6.43 6.68 6.8 ChEMBL
CB1 CNR1 Human Cannabinoid A pKi 5.75 7.02 7.96 ChEMBL
CB1 CNR1 Mouse Cannabinoid A pKi 5.27 6.16 7.05 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GPR18 GPR18 Human GPR18, GPR55 and GPR119 A pEC50 5.42 5.42 5.42 Guide to Pharmacology
GPR55 GPR55 Human GPR18, GPR55 and GPR119 A pEC50 7.74 7.74 7.74 Guide to Pharmacology
CB1 CNR1 Rat Cannabinoid A pEC50 4.8 5.59 7.16 ChEMBL
CB1 CNR1 Rat Cannabinoid A pIC50 7.4 7.4 7.4 ChEMBL
CB1 CNR1 Mouse Cannabinoid A pEC50 6.44 6.44 6.44 ChEMBL
CB1 CNR1 Mouse Cannabinoid A pIC50 4.92 6.17 7.41 ChEMBL