ancriviroc


SMILES CCO/N=C(\c1ccc(cc1)Br)/C1CCN(CC1)C1(C)CCN(CC1)C(=O)c1c(C)cc[n+](c1C)[O-]
InChIKey ZGDKVKUWTCGYOA-URGPHPNLSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 556.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Ligand site mutations CCR5

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCR5 CCR5 Human Chemokine A pKi 7.8 8.25 8.7 Guide to Pharmacology
CCR5 CCR5 Human Chemokine A pKd 8.9 8.9 8.9 Guide to Pharmacology
CCR5 CCR5 Human Chemokine A pKi 8.68 8.68 8.68 ChEMBL
CCR5 CCR5 Mouse Chemokine A pKi 8.68 8.68 8.68 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database