CHEMBL143761


SMILES N#Cc1ccc2[nH]c(CN3CCN(c4ccc(F)cc4)CC3)cc2c1
InChIKey VEYSGMPQWOSGTB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 334.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.07 5.07 5.07 ChEMBL
D4 DRD4 Human Dopamine A pKi 9.0 9.0 9.0 ChEMBL
D3 DRD3 Human Dopamine A pKi 4.82 4.82 4.82 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.55 4.62 4.72 ChEMBL
D1 DRD1 Pig Dopamine A pKi 5.07 5.07 5.07 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pEC50 8.03 8.03 8.03 ChEMBL