CHEMBL152304


SMILES O=C(NCCCCN1CCN(c2cccc(Cl)c2Cl)CC1)c1ccnc2ccccc12
InChIKey QCJZXZBQQQGNOA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 456.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 9.14 9.14 9.14 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.22 6.22 6.22 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.05 7.05 7.05 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.37 6.37 6.37 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database