CHEMBL146557


SMILES Oc1nc2ccccc2n1C1CCN(Cc2ccn(-c3ccccc3)c2)CC1
InChIKey DZKGMYCNIICGIS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 372.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Green monkey Dopamine A pKi 6.4 6.4 6.4 ChEMBL
D2 DRD2 Green monkey Dopamine A pKi 6.75 6.75 6.75 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.19 6.19 6.19 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database