CHEMBL147483


SMILES COc1cccc(C(=O)NCCN2CCN(c3ccccn3)CC2)c1
InChIKey RMGWJLOIEDIFJI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 340.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 9.2 9.2 9.2 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.57 7.57 7.57 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pIC50 9.0 9.0 9.0 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pIC50 7.52 7.52 7.52 ChEMBL