CHEMBL157322


SMILES COc1cccc(C(=O)NCCN2CCN(c3ccccc3Cl)CC2)c1
InChIKey AZSNMHBBOOLVAC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 373.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 6.84 6.84 6.84 ChEMBL
D4 DRD4 Human Dopamine A pKi 10.4 10.4 10.4 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.57 7.57 7.57 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database