CHEMBL1631532


SMILES COC(=O)Nc1cccc(CCN2CCN(c3cccc4nc(C)ccc34)CC2)c1
InChIKey WBUCFEOIQMRVHB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 404.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 9.3 9.3 9.3 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 9.6 9.6 9.6 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.6 7.6 7.6 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.7 6.7 6.7 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.0 7.0 7.0 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.7 6.7 6.7 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 9.4 9.4 9.4 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.7 6.7 6.7 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.1 6.1 6.1 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database